News of World Medicine

Insulin spray will help the people with cognitive impairment

There are more evidences that insulin performs a number of important functions in the brain. In the course of research, an insulin resistance, its decreased level in the cerebrospinal fluid and disturbed transmission of insulin signals in the brain were revealed in people suffering from Alzheimer's disease. Specialists from the University of Rush have suggested that apparently, an insulin spray will positively affect the cognitive functions in these people.

According to, the clinical study (phase II / III) will involve 275 adults aged 55 to 85 years with mild cognitive impairment or early Alzheimer's disease. The study will last 18 months. The volunteers will be divided into groups. The first group will use the insulin spray for 12 months, and the second - a placebo.

Then all participants will be given a nasal insulin spray. They will have to use it for another 6 months. The scientists plan to evaluate the safety and effectiveness of the spray. Preliminary tests have shown the improvement of cognitive functions due to the spray effect. In addition, it is possible that the effect depends on a gender.