Scientists have explained why many hereditary diseases are difficult to eradicate
So, some genetic variants that increase the risk of Alzheimer's disease or cancer do not leave from generation to generation. It turns out that the process helping people to resist pathogens, allows the problematic mutations to occur again in the genome. That is, the law of evolutionary selection does not work here, The Economic Times says.
Permanent adaptation to new pathogens has increased the diversity of the human immune genes. On the one hand, this is good. But there is another thing. Diversity in any genetic forms concerns surrounding DNA segments. There, it develops into malware variants.
For this reason, the set of genetic hereditary diseases can be associated with pathogens’ exposure. At the same time, immune gene selection process clearly increases the prevalence of different variants, even if they are dangerous.