News of World Medicine

Scientists have found a mutation that causes infertility in women

The scientists still do not know the cause of 10 to 15% of cases of infertility and 50% of cases of usual (multiple) miscarriage. Researchers from Baylor College of Medicine have revealed a new mutation that reduces women's reproductive success and fertility, Zee News says.

The study was conducted in mice. The scientists have noticed that females with "switched off" Nlrp2 gene had a number of negative consequences, including miscarriage due to abnormal development of the placenta, miscarriage prior to implantation, and (rarely) birth of posterity with developmental abnormalities.

The aforementioned mutation in males did not affect their fertility and posterity. The researchers observed the females that were carriers of the mutation. Some of them cannot become pregnant, some mice had dead cubs with anomalies, and others simply gave birth to a fewer quantity of baby mice than mice without mutation. Also, the scientists tried to grow ovicells of mice with a mutation in the laboratory, but these ovicells were not developed.

Source: Zee News.