News of World Medicine

Scientists have found a new recipe against supergerms

The scientists of the University of Oregon have revealed a molecule which is capable to neutralize the bacteria resistance to antibiotics, Xinhua reports. This molecule is known as PPMO (phosphorodiamidate morpholino oligomer). It inhibits the activity of NDM-1 enzyme which makes the bacteria resistant to penicillin.

Experiments have shown that PPMO molecule restores the efficacy of meropenem (broad-spectrum antibiotic) against bacteria with NDM-1. The combination of meropenem and PPMO copes well with pathogenic strains of E. coli, which had NDM-1.

A key element of drug resistance is common for many types of bacteria. This approach is universal. Researchers believe that PPMO molecule will be ready for human testing in three years.

Source: МEDdaily