Scientists have found a new recipe against supergerms
The scientists of the University of Oregon have revealed a molecule which is capable to neutralize the bacteria resistance to antibiotics, Xinhua reports. This molecule is known as PPMO (phosphorodiamidate morpholino oligomer). It inhibits the activity of NDM-1 enzyme which makes the bacteria resistant to penicillin.
Experiments have shown that PPMO molecule restores the efficacy of meropenem (broad-spectrum antibiotic) against bacteria with NDM-1. The combination of meropenem and PPMO copes well with pathogenic strains of E. coli, which had NDM-1.
A key element of drug resistance is common for many types of bacteria. This approach is universal. Researchers believe that PPMO molecule will be ready for human testing in three years.