INSTRUCTION FOR USE

FOOD SUPPLEMENT

ARTIKON^®

Composition: 1 flask contains: fish collagen peptide – 5000 mg (country of origin, Japan), glucosamine hydrochloride – 1500 mg, calcium gluconate – 120 mg, methylsulfonylmethane – 100 mg, hyaluronic acid – 60 mg, Uncaria tomentosa extract – 60 mg, royal jelly – 20 mg.

Excipients: purified water, isomaltooligosaccharide sweetener, sodium citrate acidity regulator, sodium benzoate preservative (E211), xanthan gum thickener, aspartame sweetener (E951), peach flavour.

Characteristics of ingredients:

Fish collagen peptide. Collagen is an extracellular protein, which is the main component of connective tissue. This collagen provides the elasticity and flexibility of connective tissue. It is a fibrillar protein of glycoprotein origin, consisting of macromolecules that have a unique trispiral structure. It is about 1/3 of all body proteins and 70% of skin protein mass. This collagen is included in the bones, tendons, blood vessels and cartilage. In the human body, it plays an important "regulatory role" in of the connective tissue functioning (qualitative composition of the cell structure, ensures the tissue flexibility and elasticity, prevents the tissue dehydration, ensures moisturizing of the deeper skin layers and slows down its aging, improves hair and nails). Fish collagen peptide is the main source of collagen in the pharmaceutical industry. Collagen peptides are small bioactive peptides obtained by enzymatic hydrolysis of fish collagen; they have a high level of security. Artikon® contains a high-quality collagen peptide, which is made in Japan.

Fish collagen peptide helps the bones to absorb calcium, as well as improves joint functioning and accelerates recovery of damage. Studies have shown that high molecular weight fractions of collagen peptide provide high mRNA synthesis of type I collagen by dermal fibroblasts. The synthesis of type I collagen is important for the optimal condition of cartilage, tendons, bone tissue, skin and blood vessels.

There has been established that fish collagen peptide has antioxidant and anti-inflammatory effects due to its impact on the activity of nitric oxide free radicals and lipoxygenase. The oral use of collagen peptide improves skin hydration and its elasticity, and reduces wrinkles as well.

Glucosamine hydrochloride is produced by the cartilage tissue of the joints. It is a component of chondroitin and is a part of the synovial fluid. Glucosamine hydrochloride stimulates the biosynthesis of glycosaminoglycans, and contributes to the restoration of cartilage tissue and the reduction of degenerative changes in the joints. It normalizes the internal joint fluid secretion, reduces sever joint pain and improves joint mobility.

Hyaluronic acid plays a significant role in the regulation of various biological processes and maintaining homeostasis, increases the elasticity of cartilage, ensures the resistance of cartilage to compression and damage. It is effective for the treatment of various types of joint diseases, including joint osteoarthritis (including the knee joint) and meniscus edema. Hyaluronic acid helps to relieve joint pain, improve the density of chondrocytes, restore the surface of the amorphous cartilage layer, remodelling collagen and increase the level of skin hydration.

Royal jelly improves tropism in tissues, reduces inflammation and processes of free radical oxidation, as well as increases the number of osteoblasts and improves bone tissue formation.

Calcium gluconate is a source of calcium. It is involved in the transmission of nerve impulses and muscle contraction.

Uncaria tomentosa reduces the progression of inflammatory processes due to polyphenolic compounds, modulates the expression of inflammatory mediators, stabilizes phospholipid membranes and has an antioxidant effect.

Methylsulfonylmethane (MSM) is a natural source of food sulphur, which plays an important role in maintaining the elasticity and flexibility of the connective tissue of the joints. Methylsulfonylmethane has anti-inflammatory and antioxidant effects by inhibiting the expression of inducible nitric oxide synthase, prostaglandin E2, cyclooxygenase-2 and interleukin-6. Also it enhances the action of glucosamine.

Recommendations for use: the product can be recommended as a source of biologically active substances, glucosamine, collagen, hyaluronic acid and calcium. It contributes to the normalization of the musculoskeletal system functioning in case of intense physical activity.

It is recommended to consult your doctor before use.

Directions: adults should take 1 flask (50 ml) per a day for one serving without additional dilution, 20-30 minutes before eating. Shake well the flask before use.

Duration for use: 1.5 to 3 months. The further period of use should be discussed with your doctor.

Precautions for use. In case of any discomfort after product administration, it is necessary to discontinue its use immediately and turn for doctor’s advice.

Warnings: do not exceed the recommended daily dose. Do not use as a substitute for a balanced diet.

Contraindications: the product is not recommended for pregnant and lactation women and people with individual hypersensitivity to the components.

Release form: 50 ml solution in a flask, 10 flasks in a box.

Storage: store in a dry, cool place protected from direct sunlight at a temperature not exceeding 25°C. Do not freeze!

Keep out of reach of children.

Shelf life: 2 years from the date of manufacture.

It is a food supplement. It contains sweeteners. It contains a source of phenylalanine

It is not a medicinal preparation. Does not contain GMO.

The country of origin of fish collagen peptide is Japan.

Manufactured by: Ananta Medicare Limited, legal address: 621, Ring Road Mall, Sector-3, Rohini, New Delhi-110085, India, tel.: +91 1147050531.

Actual manufacturing facilities (site) address: G-1-265, Phase-II, RIICO Industrial Area, Udyog Vihar, Sri Ganganagar (Raj), India.

Importer:

Ananta Medicare Ukraine Limited, 37, Iskrinska str., Kharkiv, Ukraine, 61001, tel.+38(057)739-03-09.