As Health Day notes the injectable diabetic medicine - glucagon-like peptide-1 (GLP-1) - may be released in the form of tablets. Experimental tablets have already been tested on volunteers. More than 1100 people with type 2 diabetes participated in the trials lasting 26 weeks. People were divided into several groups. In the one group, 1 mg Semaglutide injections were performed weekly. Five other groups were given different dosages orally - 2.5, 5, 10, 20 or 40 mg. Another group was given an oral dosage form of the drug with a constant increase in dosage. There was also a placebo group.
For 10 years scientists from the University of Manchester have been worked on the development of powerful inflammatory inhibitors. They have managed to create compounds that suppress the activity of inflammasomes - protein complexes that trigger an inflammatory reaction in many types of cancer, Alzheimer's disease and cardiovascular diseases, The Deccan Chronicle reports.
As Zee News notes, scientists have revealed an antibody that prevents Dengue and Zika viruses. As we know the first virus causes headaches, fever and muscle pains. The second virus is dangerous for children. In case of infection of a pregnant woman the virus causes birth defects.
A lot of tumors protect themselves from the body's immune system by creating a barrier from tangled blood vessels. Those vessels feed the tumor and prevent the immune cells to attack the tumor. As Medical Xpress notes, scientists of the University of Western Australia and Harry Perkins Medical Research Institute have developed a new remedy that can solve this problem.
According to scientists from the University of Maryland, the protein is called retrocyclin-101 (RC-101). As The Times of India notes, the protein is unique. It not only affects the influenza virus, but also affects the inflammation occurred.
A lot of women with breast cancer have to undergo unnecessary chemotherapy. Scientists have developed a new test for women with ER +/HER2-breast cancer called Oncotype DX. It shows the likelihood of a recurrence of cancer. As Zee News notes, the tumor samples removed during the surgery are needed for the test.
Scientists of the University of Pennsylvania have approached the creation of a new method against cancer. The target of the scientists was the lysosomal enzyme PPT1. As Zee News notes the experts have already developed a drug that effectively fights melanoma, pancreatic cancer and colorectal cancer in mice.
Scientists of the University of Southern California have analyzed the data of 4,890 people with autism spectrum disorders (ASD). The experts have revealed eight mutations in TRIO gene, which play an important role in the development of autism. These mutations cause a chain reaction. They break the connection between the brain cells as well as the ability to store and process information.
Scientists from the University of Oregon have revealed two proteins that may help to create a vaccine against gonorrhea. Gonococcus (gonorrhea causative agent) is a super-bacterium that is resistant to all existing antibiotics. Therefore, the appearance of the vaccine will be a real breakthrough, Medical Xpress reports.
A study conducted by Northwestern University has shown that weekly administration of glucocorticoid steroids, such as prednisone, helps to accelerate recovery in muscle injuries. As Xinhua notes, this conclusion is based on the results of experiments in rodents. But, according to the scientists, the discovery will be useful for the therapy of people with muscular dystrophy.